3/1/2024 0 Comments Digibind antidote![]() 3 Since human experience is limited and the consequences of repeated exposures are unknown, DIGIBIND is not indicated for milder cases of digitalis toxicity. ![]() 3 Although designed specifically to treat life-threatening digoxin overdose, it has also been used successfully to treat life-threatening digitoxin overdose. The antibody is then papain-digested and digoxin-specific Fab fragments of the antibody are isolated and purified by affinity chromatography.ĭIGIBIND, Digoxin Immune Fab (Ovine), is indicated for treatment of potentially life-threatening digoxin intoxication. Sheep are immunized with this material to produce antibodies specific for the antigenic determinants of the digoxin molecule. Production of antibodies specific for digoxin involves conjugation of digoxin as a hapten to human albumin. Summary Description and Clinical Pharmacology Indications and Dosage Warnings and Precautions Side Effects and Adverse Reactions Drug Interactions, Overdosage, Contraindications, Other Rx Info Active IngredientsĭIGIBIND, Digoxin Immune Fab (Ovine), is a sterile lyophilized powder of antigen binding fragments (Fab) derived from specific antidigoxin antibodies raised in sheep. Rx drug information, pharmaceutical research, clinical trials, news, and moreĭigibind (Digoxin Immune Fab (Digoxin Antidote)) - Summary Digibind (Digoxin Immune Fab) - Drug Info, Side Effects, Research, Clinical Trials
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